Karma (from Advayavada website)

Karma, we must stress, is, in our view, pratityasamutpada or dependent origination at our sentient level, including personal choices and responsibility - it is the immanent universal dynamic principle of existence as it also operates incessantly within the human being, in the relations between all sentient beings and in their interaction with the environment. Wholesome human activities are necessarily those which are in agreement with the overall otherwise indifferent pattern and direction of existence. It is, indeed, for this reason that they are experienced by us as such. You will no doubt agree that there cannot be two sets of rules at play, one for totality and one as devised by humankind itself for its own affairs only.

QUESTION What do you mean by 'indifferent'?

ANSWER The same idea of the indifference of Nature to the concerns of humanity is, for instance, also treated in chapter 5 of the Tao Te Ching ("Heaven and Earth are not humane, they regard all things as straw dogs, etc."), which please see in your copy of this important book.